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Safety of Cerebrolysin for neurorecovery after acute ischemic stroke: a systematic review and meta-analysis of twelve ran-domized-controlled trials

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Description: Cerebrolysin is recommended in clinical practice guidelines across several continents. Previous meta-analyses on Cerebrolysin safety profile provided inconsistent results. This applies especially to the two largest most recent meta-analyses: Bornstein et al. 2018, including 1879 patients from nine randomized-controlled trials (RCTs), and the review of Ziganshina et al. 2020, including 1601 patients from seven RCTs. To resolve the reported discrepancies, the present meta-analysis aimed to explore the safety profile of Cerebrolysin, using the maximum amount of evidence available.

License: CC-By Attribution-ShareAlike 4.0 International

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