Target of replication: *A priori* experimental protocols, materials, and confirmatory analysis plans were peer reviewed, [pre-registered][1], and published by [*eLife*][2]. This component includes all primary and QC data for the replication of [Poliseno et al., 2010][3]. ### Contents ### [Figures component][4] contains a visualization of the results. These figures are the same as can be found in the Replication Study and include Figure 1. [Data Component][5] contains data generated from the experimental work. [Statistical Analysis Component][6] contains the R scripts used for the analysis. [Methods Component][7] contains detailed methods used in the experimental work. [Cell line quality Control data][8] includes results confirming the cell line was free of mycoplasma as well as STR DNA profiling. [PTEN 3'UTR plasmid][9] includes data and methods for the generation of the plasmid that is deposted at [https://www.addgene.org/97204/][10] [1]: https://osf.io/2evzy [2]: https://elifesciences.org/articles/08245 [3]: https://doi.org/10.1038/nature09144 [4]: https://osf.io/ruphc/wiki/home/ [5]: https://osf.io/qf7xa/wiki/home/ [6]: https://osf.io/mavh2/wiki/home/ [7]: https://osf.io/8xfzk/wiki/home/ [8]: https://osf.io/b4rt2/wiki/home/ [9]: https://osf.io/9stbg/ [10]: https://www.addgene.org/97204/