This component includes data and analysis scripts for the meta-analyses of the effects from the experiment reported in Figure 4C and Supplemental Figure 1 of [Sirota et al. 2011][1] and the replication of this experiment. **Figure 3 . Meta-analyses of each effect.** Effect size (Cohen’s *d*) and 95% confidence interval are presented for Sirota et al., 2011, this replication attempt (RP:CB), and a meta-analysis to combine the two effects of day 11 tumor volume comparisons. Sample sizes used in Sirota et al., 2011 and this replication attempt are reported under the study name. Random effects meta-analysis of A549-derived tumors treated with vehicle (PBS) compared to 100 mg/kg cimetidine (meta-analysis *p* = .0043), ACHN-derived tumors treated with vehicle (PBS) compared to 100 mg/kg cimetidine (meta-analysis *p* = .917), and A549-derived tumors treated with vehicle (PBS) compared to 2 mg/kg doxorubicin (meta-analysis *p* = .021). Access [full size image][3] and [R script][4] used to generate this figure. These scripts will call the [data][5] directly from the OSF. Access [analysis script][6]. This script will call the [data][7] directly from the OSF for the replication data. [1]: http://stm.sciencemag.org/content/3/96/96ra77 [3]: https://osf.io/ycq5g/ [4]: https://osf.io/fguas/ [5]: https://osf.io/nvhp2/ [6]: https://osf.io/dnc4e/ [7]: https://osf.io/46zcg/