Target of replication: *A priori* experimental protocols, materials, and confirmatory analysis plans were peer reviewed, [pre-registered][1], and published by [*eLife*][2]. This component includes all primary and QC data for the fourth protocol of the replication of [Vermeulen et al., 2010][3]. These experiments include: ### Contents ### [Statistical Analyses component][4] contains R scripts that were used for the analysis, with results reported in Table 1 of the [Replication Study][5]. [Data Component][6], contains data generated from the experimental work related to Protocol 4 of the Registered Report (*in vivo* tumorigenicity assay) [Methods Component][7], contains the methods relating to Protocol 4 of the Registered Report (*in vivo* tumorigenicity assay) [1]: https://osf.io/rscpj/ [2]: https://elifesciences.org/articles/07301 [3]: https://www.nature.com/articles/ncb2048 [4]: https://osf.io/9qdbu/wiki/home/ [5]: https://elifesciences.org/articles/45426#info [6]: https://osf.io/y8skb/wiki/home/ [7]: https://osf.io/ecxnm/wiki/home/