Individual Differences in Dopamine are Associated with Reward Discounting in Clinical Groups but not in Healthy Adults

Affiliated institutions: Duke University

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Description: Reward discounting and dopamine D2-like receptor availability

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Abstract: Some people are more willing to make impulsive, risky, or costly choices than others, which has been assumed to be strongly associated with individual differences in dopamine (DA) function. In two studies using PET imaging, one empirical (Study 1: N=144) and one meta-analytic (Study 2: N=332), we sought to characterize associations between individual differences in DA and time, probabili...

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