Data dictionary
1. Lesion maps
Resection, resection+, and residual lesion maps in MNI space generated via the Clinical Toolbox in SPM12
Resection maps: *lesion.nii
Resection+ maps: *lesionplus.nii
Residual maps: *lesionresid.nii
2. Data files
Participant demographic and QOL scores, tractwise-disconnection severities
QoL_PCA.csv
QOL scores from Comprehensive Aphasia Test Disability Questionnaire (CAT-DQ), Functional Assessment of Cancer Therapy-Brain (FACT-Br), Depression, Anxiety and Stress Scale (DASS-21), as well as principal component scores from principal component analysis across all QOL measures
Variables
- Subject = subject ID
- Filename = filename
- post_dass_d_21 = DASS-21 depression score
- post_dass_a_21 = DASS-21 anxiety score
- post_dass_s_21 = DASS-21 stress score
- post_fact_pwb_28 = FACT-Br personal well-being score
- post_fact_swb_28 = FACT-Br social/family well-being score
- post_fact_ewb_24 = FACT-Br emotional well-being score
- post_fact_fwb_28 = FACT-Br functional well-being score
- post_fact_cs_92 = FACT-Br cancer-subscale score
- post_fact_toi_148 = FACT-Br trial-outcome-index score
- post_fact_g_108 = FACT-Br general score
- post_fact_total_200 = FACT-Br total score
- post_cat_dis_t_16 = CAT-DQ disability expression score
- post_cat_dis_u_16 = CAT-DQ disability comprehension score
- post_cat_dis_r_16 = CAT-DQ disability reading score
- post_cat_dis_w_16 = CAT-DQ disability writing score
- post_cat_dis_d_total_64 = CAT-DQ disability total score
- post_cat_dis_i_16 = CAT-DQ impact intrusion score
- post_cat_dis_si_16 = CAT-DQ impact self-image score
- post_cat_dis_ec_28 = CAT-DQ impact emotional consequences score
- post_cat_dis_imp_total_60 = CAT-DQ impact total score
- post_cat_DQ_124 = CAT-DQ disability quotient score
- sex = 1/2 (1 = female, 2 = male)
- age = age in years
- edu = education in years
- WHO = WHO grade (1-4)
- post = time post surgery in days
- Score Component 1 = QOL PCA1 (communication-related component)
- Score Component 2 = QOL PCA2 (mood-related component)
- Score Component 3 = QOL PCA3
QoL_disconnection_[lesion-map].csv
Data for tract-wise disconnection severity analysis
Variables
- Filename = file name
- PCA1 = QOL PCA1 (communication-related component)
- PCA2 = QOL PCA2 (mood-related component)
- sex = 1/2 (1 = female, 2 = male)
- age = age in years
- edu = education in years
- WHO = WHO grade (1-4)
- post = time post surgery in days
- AF_L = percentage disconnected streamlines in left arcuate fasciculus
- FAT_L = percentage disconnected streamlines in left frontal aslant tract
- IFOF_L = percentage disconnected streamlines in left inferior fronto-occipital fasciculus
- ILF_L = percentage disconnected streamlines in left inferior longitudinal fasciculus
- UF_L = percentage disconnected streamlines in left uncinate fasciculus
- lesionplusvol = residual tumor volume
3. Statistical analysis
Statistical analyses conducted in JAMOVI
QoL_PCA_KLM.omv
Principal component analysis conducted across 10 QOL measures
QoL_[lesion-map]_tractwise_disconnection_EK.omv
Regression analyses of tract-wise disconnection severities and QOL components
