# Data dictionary ## 1. Lesion maps *Resection, resection+, and residual lesion maps in MNI space generated via the Clinical Toolbox in SPM12* **Resection maps:** *lesion.nii **Resection+ maps:** *lesionplus.nii **Residual maps:** *lesionresid.nii ## 2. Data files *Participant demographic and QOL scores, tractwise-disconnection severities* ### QoL_PCA.csv QOL scores from Comprehensive Aphasia Test Disability Questionnaire (CAT-DQ), Functional Assessment of Cancer Therapy-Brain (FACT-Br), Depression, Anxiety and Stress Scale (DASS-21), as well as principal component scores from principal component analysis across all QOL measures **Variables** - Subject = subject ID - Filename = filename - post_dass_d_21 = DASS-21 depression score - post_dass_a_21 = DASS-21 anxiety score - post_dass_s_21 = DASS-21 stress score - post_fact_pwb_28 = FACT-Br personal well-being score - post_fact_swb_28 = FACT-Br social/family well-being score - post_fact_ewb_24 = FACT-Br emotional well-being score - post_fact_fwb_28 = FACT-Br functional well-being score - post_fact_cs_92 = FACT-Br cancer-subscale score - post_fact_toi_148 = FACT-Br trial-outcome-index score - post_fact_g_108 = FACT-Br general score - post_fact_total_200 = FACT-Br total score - post_cat_dis_t_16 = CAT-DQ disability expression score - post_cat_dis_u_16 = CAT-DQ disability comprehension score - post_cat_dis_r_16 = CAT-DQ disability reading score - post_cat_dis_w_16 = CAT-DQ disability writing score - post_cat_dis_d_total_64 = CAT-DQ disability total score - post_cat_dis_i_16 = CAT-DQ impact intrusion score - post_cat_dis_si_16 = CAT-DQ impact self-image score - post_cat_dis_ec_28 = CAT-DQ impact emotional consequences score - post_cat_dis_imp_total_60 = CAT-DQ impact total score - post_cat_DQ_124 = CAT-DQ disability quotient score - sex = 1/2 (1 = female, 2 = male) - age = age in years - edu = education in years - WHO = WHO grade (1-4) - post = time post surgery in days - Score Component 1 = QOL PCA1 (communication-related component) - Score Component 2 = QOL PCA2 (mood-related component) - Score Component 3 = QOL PCA3 ### QoL_disconnection_[lesion-map].csv Data for tract-wise disconnection severity analysis **Variables** - Filename = file name - PCA1 = QOL PCA1 (communication-related component) - PCA2 = QOL PCA2 (mood-related component) - sex = 1/2 (1 = female, 2 = male) - age = age in years - edu = education in years - WHO = WHO grade (1-4) - post = time post surgery in days - AF_L = percentage disconnected streamlines in left arcuate fasciculus - FAT_L = percentage disconnected streamlines in left frontal aslant tract - IFOF_L = percentage disconnected streamlines in left inferior fronto-occipital fasciculus - ILF_L = percentage disconnected streamlines in left inferior longitudinal fasciculus - UF_L = percentage disconnected streamlines in left uncinate fasciculus - lesionplusvol = residual tumor volume ## 3. Statistical analysis *Statistical analyses conducted in JAMOVI* ### QoL_PCA_KLM.omv Principal component analysis conducted across 10 QOL measures ### QoL_[lesion-map]_tractwise_disconnection_EK.omv Regression analyses of tract-wise disconnection severities and QOL components