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Functionalization and biological responses to polydopamine coatings
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Description: Polydopamine has gained a lot of interests over the past 10 years due to its outstanding adhesion properties and functionalization abilities. By a simple dip-coating method, PDA can stick to almost any material and are described in literature as way of improving the biocompatibility of material surfaces. However, we have found that the surface chemistry of the PDA coating changes depending on the environment thus altering its biocompatibility. The aim of this project is to study the change in the functional groups at the surface (amines, catechols) by heat-treatment of the polydopamine coatings. The heat treatment is importent within the field of biomaterials, as they have to be sterilized before use (especially by an autoclave (heat)).