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Replication Studies  /

Affiliated institutions: Center For Open Science

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Category: Project

Description: Replication of "Widespread potential for growth-factor-driven resistance to anticancer kinase inhibitors”. Includes information to prepare the replication experiments. Includes data, code, and digital materials from started, but incompleted replication experiments.

License: CC-By Attribution 4.0 International

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Type: Individual replications
Status: Incomplete


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Original paper:
Wilson T.R., Fridlyand J., Yan Y., Penuel E., Burton L., Chan E., Peng J., Lin E., Wang Y., Sosman J., Ribas A., Li J., Moffat J., Sutherlin D.P., Koeppen H., Merchant M., Neve R., Settleman J. Widespread potential for growth-factor-driven resistance to anticancer kinase inhibitors. Nature. 2012 Jul 26;487(7408):505-9. doi: 10.1038/nature11249.


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Registered Report Additional Materials

Greenfield, Griner, Iorns & 4 more

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Cancer BiologyMethodologyReceptor Tyrosine Kinase inhibitorReplicationReproducibility Project: Cancer BiologySignaling pathway reactivation

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