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One main purpose of information architecture and site navigation is to enhance the effectiveness of user interfaces (UIs) by supporting and enabling task completion, accessibility, and sustainability. This is of particular importance for science gateways given the complexity of information on portal sites. We examined the accessibility of 50 randomly selected gateway websites in the Life Sciences category in the Science Gateways Community Institute (SGCI) catalog, using both manual and automated methodologies. None of these sites produced an accessible website as per W3C, WCAG 2.1, and Section 508 standards. The most common accessibility success in these websites was URL structure, which enables web browsers and search engines to access content.
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