**Principal Investigator(s):** Rebecca Ferrer National Cancer Institute Email: [ferrerra@mail.nih.gov][1] William M. P. Klein National Cancer Institute Email: [kleinwm@mail.nih.gov][2] **Sample size:** 419 **Field period:** 01/29/2014-03/17/2015 **Hypotheses:** H1: Consistent with previous research, self-affirmation will reduce defensiveness and increase the persuasiveness of the personally threatening message, compared to control. Thus, self-affirmed participants reading the personally threatening message should report higher deliberative and affective risk perception profiles, greater message endorsement, higher message recall, and greater intentions to talk to a doctor and engage in a hypothetical screening. H2: Among the non-affirmed participants, those reading a threatening message related to a close other should be less defensive and more persuaded than those reading a personally threatening message. Among non-affirmed participants who read the other-threatening message (compared to those who read the personally threatening message), deliberative and affective risk perception measures, message endorsement, message recall, and intentions to encourage the close other to talk to a doctor and engage in a hypothetical screening should be higher. **Experimental Manipulations:** Self-affirmation vs. no affirmation Threatening message for close other vs. for self **Key Dependent Variables:** Risk perceptions, interest in information, interest in testing, weight loss intentions **Summary of Findings:** We uncovered a relatively strong self-other difference for experiential and affective risk perceptions, interest in more information, and interest in testing, such that people are more concerned about their partner than they are about themselves. At the same time, they show more intentions to lose weight themselves than to encourage their partner to lose weight. These effects do not interact with self-affirmation in the overall sample. Among females, self-affirmation makes them more likely to believe the website info, have interest in more information, and perceive the website information to be more relevant, irrespective of whether the information is about them or their partner (no interaction with target – self or other). **Findings from this study:** Klein, W. M., & Ferrer, R. A. (2018). On Being More Amenable to Threatening Risk Messages Concerning Close Others (vis-a-vis the Self). Personality and Social Psychology Bulletin, 44(10), 1411-1423. [1]: mailto:ferrerra@mail.nih.gov [2]: mailto:kleinwm@mail.nih.gov