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Category: Project

Description: There’s evidence that transcranial Alternating Current Stimulation (tACS) is able to modulate brain activity, but its exact mechanisms are still unclear (Fröhlich & McCormick, 2010). It is hypothesized that entrainment according to the theory of synchronization (Pikovsky, Rosenbaum & Kurths, 2003) is the underlying mechanism. Evidence of this has been found in animals and in humans (Huang et al., 2021; Krause, Vieira, Csorba, Pilly & Pack, 2019). It is unclear if similar effects would be found with different types of stimulation. There is some evidence that Transcranial Temporal Interference Stimulation (tTIS) follows the principles of synchronization theory (Esmaeilpour, et al., 2021). In addition, due to its oscillatory nature, it could be expected that tTIS would produce similar entrainment effects as tACS (Notbohm, Kurths & Herrmann, 2016). This study aims to show entrainment of human alpha oscillations to tTIS by recovering online EEG recordings during stimulation and exploring entrainment echoes immediately after the offset of stimulation.