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Description: Background: Postoperative knee swelling (PKOS) following anterior cruciate ligament reconstruction (ACLR) is known to contribute to deficits such as pain, swelling, reduced range of motion, and strength, impeding quadriceps activation, inducing arthrogenic muscle inhibition, and delaying rehabilitation. This study aimed to explore the association of PKOS with pain, range of motion, maximum voluntary contraction, and functional outcome after ACLR. Methods: Thirty-two subjects undergoing ACLR were recruited for this study. PKOS, pain, range of motion, and maximum voluntary contraction were measured on days 0, 1, 2, 3, 2nd week, and 6th week, while functional outcome was assessed using the Lower Extremity Functional Scale (LEFS) after 2 weeks and 6 weeks. Girth measurement was taken to assess swelling, pain was assessed using visual analog scale, and maximum voluntary contraction was analyzed using surface electromyography. Results: Mean values for PKOS, visual analog scale, range of motion, maximum voluntary contraction, and functional outcome showed overall improvement from day 0 to week 6, except for maximum voluntary contraction values which exhibited fluctuations from day 2 to day 3. However, no significant association (p > 0.05) was found between PKOS and pain, range of motion, maximum voluntary contraction, and functional outcome. Conclusion: While PKOS improved along with other variables over the recovery period, it exhibited no significant correlation with pain, range of motion, strength, or functional outcome post-ACLR, warranting further investigation.