![enter image description here] : https://www.bihealth.org/fileadmin/_processed_/f/4/csm_PREMIER_LOGO_c7b63f357d.jpg ‘PREMIER’ (Productiveness and Robustness through Modular Improvement of Experimental Research), is intended as a set of freely available “building blocks” of quality-ensuring measures tailored to academic biomedicine. These will be user-friendly, modular, scalable, practicable, financeable and acceptable for scientists. The proposed measures will be accessible as open source in the form of documents, instructions, guides, tools and training modules. Compliance will be demonstrable through a review process. With PREMIER, we aim to provide a framework for easy entry to a modular QM system, which can be implemented in workgroups, departments, or even institutions to systematically improve the quality of academic preclinical biomedical research.