## Description of contents ##
This repository contains data and code for the manuscript *Applying genome-wide CRISPR to identify known and novel genes and pathways that modulate formaldehyde toxicity* by Yun Zhao et al. available at [https://doi.org/10.1016/j.chemosphere.2020.128701][1].
- **Raw data:** Next generation sequencing count data for various CRISPR probes after 8 or 20 days of exposure to 40, 100, or 150 μM formaldehyde
- **edgeR results:** Test statistics produced by using BioConductor's *edgeR* package to detect significant differences between control and exposed cell populations
- **Code:** Example code to produce results in the **edgeR results** folder from the count data in the **Raw data** folder
Select CRISPR screen datasets are also available on BioGRID ORCS:
- [8 days 100 µM Formaldehyde][2]
- [8 days 150 µM Formaldehyde][3]
[1]: https://doi.org/10.1016/j.chemosphere.2020.128701
[2]: https://orcs.thebiogrid.org/Screen/1396
[3]: https://orcs.thebiogrid.org/Screen/1397