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Assessment of fruit and vegetables intake with biomarkers in children and adolescents and their level of validation: A systematic review
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Description: Fruit and vegetable are part of a healthy diet and should be frequently consumed already at young age. However, intake of fruit and vegetable (FV) is difficult to assess in children and adolescents due to various misreporting aspects. Thus, measurement of dietary biomarkers may be a promising alternative to assess FV intake more objectively at young age. To date, dietary biomarkers have been primarily studied in adults and research focused on their usefulness in children is scarce. However, clinical studies have revealed important differences between children and adults, most importantly in their gut microbiome composition resulting in differences in postprandial metabolism, as well as in food choices and meal compositions that may influence individual biomarker levels. Therefore, the present review aimed to identify biomarkers of FV intake (BFVI) currently available in children and adolescents and to explore if there are any differences of the BFVI profile above between children and adolescents, and adults. In addition, the current level of validation of BFVI in children and adolescents was examined.