Abstract: When people are confronted with reminders to an experience they would rather choose to forget, they often try to engage in the process to prevent that unwanted memory from entering into one's awareness. This process is known as retrieval suppression, is known to engage the right prefrontal cortex (PFC) and the hippocampus. However, whether the right PFC is causally necessary for retrieval stopping is a question that is still being explored in research. In this study, we adapted the Think/No-Think task for patients with brain lesions (i.e. patient-friendly- TNT). 50 patients with unilateral frontal lesions (25 left and 25 right-sided lesions) completed the task. All patients engaged in these cognitive tasks and patients with left PFC damage had little effect on suppression induced forgetting, while, damage to the right PFC fully abolished it. These findings support the suppression-induced forgetting requires the right PFC, which may be causally necessary for motivated forgetting. Patients with left frontal lesions suppressed unwanted memories (p < .001) compared to those with right lesions who were not able to supress (p = .408). These results support clinical rehabilitation and will inform strategies to cope with unwanted memories post stroke, especially to networks supporting inhibition. -- Dr Shanti Shanker, CPsychol FHEA Global Engagement Lead (GEL) Lecturer, Department of Psychology, Bournemouth University, Poole House (P250), Talbot Campus, Poole, Dorset BH12 5BB Mobile: +44 (0) 7407023620 Phone: +44(0)1202965533 Skype id: sitnahs sshanker@bournemouth.ac.uk Honorary Associate Psychologist, Acquired Brain Injury Rehabilitation Service and Adult Neuropsychology Service DHUFT. ------------------------------------------ Researcher, Social, Cognitive, Clinical and Affective Neuroscience (SCCAN) Associate Member, Ageing and Dementia Research Centre (ADRC) | www.bournemouth.ac.uk/adrc ---- Office Hours (Book Online): https://calbird.com/shanti/officehours ________________________________ BU is a Disability Confident Employer and has signed up to the Mindful Employer charter. Information about the accessibility of University buildings can be found on the BU AccessAble webpages. This email is intended only for the person to whom it is addressed and may contain confidential information. If you have received this email in error, please notify the sender and delete this email, which must not be copied, distributed or disclosed to any other person. Any views or opinions presented are solely those of the author and do not necessarily represent those of Bournemouth University or its subsidiary companies. Nor can any contract be formed on behalf of the University or its subsidiary companies via email.