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Stephen Horrigan; Elizabeth Iorns; Stephen Williams; Nicole Perfito; Timothy M. Errington

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Engraftment of mouse breast cancer cells and treatment with CD47 targeted antibodies /

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Affiliated institutions: Center For Open Science

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License: CC-By Attribution 4.0 International

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Figure 1. Blood toxicity analysis. Female FVB mice bearing orthotopic MT1A2 breast tumors were randomized to receive IgG isotype control (IgG) (n=7) or anti-mouse CD47 (CD47) (n=7) antibodies. Mice bearing small or undetectable tumors were designated for baseline reading (NT) (n=6). Five days after the beginning of treatment blood samples collected via retro-orbital bleed were analyzed on a hemato…

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