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Contributors:
  1. Shing Lee
  2. Jonathan W B Martin
  3. Thubeena Manickavasagar
  4. Rong Liu
  5. Andrew Kightley
  6. Johann De Bono

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Category: Project

Description: DF-CONSORT: protocol for the rapid methodological review

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Abstract

Objective: The objective of this methodological review is to assess the quality of reporting in early phase dose-finding clinical trials (EPDF trials), identify gaps in the reporting of such trials, and inform the development of an extension of the CONSORT statement for EPDF trials.

Introduction: Incomplete, unclear, or inaccurate reporting of the design, conduct, methods and results of E…

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Clinical trialsdose escalationdose-findingearly phasephase I

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