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Description: Imam Kazim's [IMAM Musa al-Kazim (seventh Imam in Twelver Shia Islam)] medicine consists of: 1. Foeniculum Vulgare 2. Mastic 3. Terminalia Chebula 4. Brown Sugar or the sugar, prepared from Saccharum Officinarum (Sugarcane) According to the narration narrated by Hasan Ibn Bastam Ibn Sabur (Shapur), known as Ibn Bastam, one day Imam Musa Kazim fell ill and the doctors prescribed various medicines for him. Imam said, "Where are you going? Use this medicine, which is the master of medicine. Terminalia Chebula, Foeniculum Vulgar, Brown Sugar at the beginning of summer for three months, and three times a month, also at the beginning of winter for three months and three times a month, and instead of Foeniculum Vulgare uses Mastic." "So you will not get sick until you die." Purpose: Ivermectin is a broad-spectrum antiparasitic and an effective drug to treat COVID-19. In this article, we looked at the effects of ivermectin on coronavirus and its patients in three ways. We have discussed and organized other previously discovered potential therapies and reviewed them in Table 2 and in the last section. Methods: We searched for articles on MedRxiv, PubMed, Google Scholar, MEDLINE, EMBASE uses the appropriate search terms. ClinicalTrials.gov was searched for available clinical trials evaluating the effectiveness of ivermectin. We also use EU clinical trial registry data and ANZ registry data for clinical trials. Also, we performed our methods in 4 stages: Identifying studies, Selection of Studies, Collating Studies, Reporting results. Results: Results are variable. Some studies have shown the effectiveness of ivermectin, others have not. Furthermore, some studies show that a combination of ivermectin with other drugs is useful. Conclusion: Overall, we believe the reason ivermectin is useful is that it goes back to its origin, which is soil. Our theory and hypothesis is that if the coronavirus, created by man or by nature, can generally be treated with nature, that is, the soil. The interesting thing is that today we know that ivermectin is effective in the fight against the coronavirus. In fact, other drugs like teicoplanin, cyclosporine and rapamycin that are effective against the coronavirus have come from the soil. We hope that this article has been able to take a step in finding a corona drug, InshaAllah.