Experimental Design Modulates Variance in BOLD Activation: The Variance Design General Linear Model

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Abstract Blood-oxygen-level-dependent (BOLD) activity can be described by its first and second order statistical properties. Typical studies analyze first order relationships between the BOLD time course and experimental condition--i.e., increases or decreases in BOLD activation are related to a particular experimental state. More recent fMRI studies have studied relationships involving second ord...

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