This component includes data and analysis scripts for the meta-analyses of the effects from the experiment reported in Figures 2A-C of [Ward et al., 2010][1] and the replication of this experiment. **Figure 4. Meta-analyses of each effect.** Effect size and 95% confidence interval are presented for Ward et al., 2010, this replication study (RP:CB), and a random effects meta-analysis of those two effects. Sample sizes used in Ward et al., 2010 and this replication attempt are reported under the study name. Random effects meta-analysis of AML patient samples with an IDH1 mutation compared to a constant of 0.01 (1% 2HG/glutamate level) (meta-analysis p = .214), AML patient samples with an IDH2 mutation compared to a constant of 0.01 (meta-analysis p = .011), and AML patient samples with an IDH1 or IDH2 mutation compared to a constant of 0.01 (meta-analysis p = .012). Additional details for these meta-analyses can be found at https://osf.io/4m3n8/. Access [full size image][2] and [R script][3] used to generate this figure. These scripts will call the [data][4] directly from the OSF. Access [analysis script][5]. [1]: http://www.cell.com/cancer-cell/abstract/S1535-6108%2810%2900036-X [2]: https://osf.io/pdsr9/ [3]: https://osf.io/t5gf9/files/ [4]: https://osf.io/atnbu/ [5]: https://osf.io/jg4cu/