This folder contains additional materials relating to the Registered Report for Study 50: Castellarin et al. 2012, Genome Research. The Registered Report can be found [here][1]. ---------- **Registered Report Initial Draft**: - This document represents the first draft of the selected experimental protocols. It contains the information that the Core team, with help from scientist volunteers, was able to glean from the original publication and its supplemental materials before the original authors were contacted for their input. - [Study 50 Registered Report Initial Draft][2] **Data Estimation**: - When original data was unable to be obtained, or original qualitative data was quantified (for example, Western blots), the estimated data is contained here. Examples include densitometric quantification of Western blot bands, or estimations of means and variances from published graphs. - [Study 50 Data Estimation][3] **Power Calculations**: - These documents contain details about how power calculations were performed, and include spreadsheets documenting statistical tests as well as any PRISM files, R scripts or additional materials used. - [Study 50 power calculations][4] - [Study 50 Figure 2 ratio t-test.R][5] [1]: http://elifesciences.org/collections/reproducibility-project-cancer-biology [2]: https://osf.io/v6t3n/ [3]: https://osf.io/sf74z/ [4]: https://osf.io/kxstg/ [5]: https://osf.io/bjgn5/