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Description: This study aims to compare the effects of individualised full knee flexion ROM versus 100 degrees flexion ROM in the leg press exercise on muscle thickness of the quadriceps musculature in strength-trained individuals. The hypothesis is that both coniditions will result in similar muscle thickness increases. The study will involve 25 strength-trained men and women aged 18-50 years, each with a minimum of three years of resistance training experience and training at least twice a week. Participants will undergo a 10-week training intervention with 8 weeks of resistance training, including two supervised sessions per week. Each session will consist of 4 sets per exercise all weks, with all sets performed to momentary failure. Muscle thickness will be measured using ultrasound at both proximal, middle and distal sites of the mid-thigh and lateral thigh before and after the intervention. The study design is within-subject, with limbs randomly assigned to the knee flexion ROMs. To ensure consistency, participants will not train other leg exercises that could influence the results. The study aims to provide insights into the effectiveness of different knee flexion ranges in hypertrophy training, contributing to optimized training strategies for muscle growth. Data will be shared openly after publication to ensure transparency and reproducibility.

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